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Proteins

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You may have been told proteins are good for you. Do these bugs look good to you?

Proteins as food. To you, these may not look appetizing (or they might), but they do provide a nice supply of amino acids, the building blocks or subunits of proteins. Proteins have many important roles, from transporting, signaling, receiving, and catalyzing to storing, defending, and allowing for movement. Where do you get the amino acids needed so your cells can make their own proteins? If you cannot make it, you must eat it.

Proteins

A protein is an organic compound because its made of carbon and is made up of small molecules called amino acids . There are 20 different amino acids commonly found in the proteins of living organisms which are bonded together by peptide bonds . Small proteins may contain just a few hundred amino acids, whereas large proteins may contain thousands of amino acids. The largest known proteins are the titins, found in muscle, which are composed from almost 27,000 amino acids.

General Structure of Amino Acids. This model shows the general structure of all amino acids. Only the side chain, R, varies from one amino acid to another. For example, in the amino acid glycine, the side chain is simply hydrogen (H). In glutamic acid, in contrast, the side chain is CH 2 CH 2 COOH. Variable side chains give amino acids acids different chemical properties. The order of amino acids, together with the properties of the amino acids, determines the shape of the protein, and the shape of the protein determines the function of the protein. KEY: H = hydrogen, N = nitrogen, C = carbon, O = oxygen, R = variable side chain

Protein Structure

When amino acids bind together, they form a long chain called a polypeptide . A protein consists of one or more polypeptide chains. A protein may have up to four levels of structure. The lowest level, a protein’s primary structure, is its sequence of amino acids. Higher levels of protein structure are described in Figure below . The complex structures of different proteins give them unique properties, which they need to carry out their various jobs in living organisms. 

Protein Structure. The structure of a protein starts with its sequence of amino acids. What determines the secondary structure of a protein? What are two types of secondary protein structure?

Functions of Proteins

Proteins play many important roles in living things. Some proteins help cells keep their shape, and some make up muscle tissues. Enzymes are proteins that speed up chemical reactions in cells. Another protein is Insulin which helps your body's cells absorb glucose. People who do not produce the correct amount of insulin have the disease diabetes.  Still other proteins carry messages or materials. For example, human red blood cells contain a protein called hemoglobin , which binds with oxygen. Hemoglobin allows the blood to carry oxygen from the lungs to cells throughout the body. A model of the hemoglobin molecule is shown in Figure below .

Hemoglobin Molecule. This model represents the protein hemoglobin. The red parts of the molecule contain iron. The iron binds with oxygen molecules.

Proteins and Diet

Proteins in the diet are necessary for life. Dietary proteins are broken down into their component amino acids when food is digested. Cells can then use the components to build new proteins. Humans are able to synthesize all but eight of the twenty common amino acids. These eight amino acids, called essential amino acids , must be consumed in foods. Like dietary carbohydrates and lipids, dietary proteins can also be broken down to provide cells with energy.

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