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13.1: Organization of the Human Body

Difficulty Level: At Grade Created by: CK-12
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How is the human body similar to a well-tuned machine?

Many people have compared the human body to a machine. Think about some common machines, such as drills and washing machines. Each machine consists of many parts, and each part does a specific job, yet all the parts work together to perform an overall function. The human body is like a machine in all these ways. In fact, it may be the most fantastic machine on Earth.

As a preview of the human machine, the Emmy award-winning video, Inside The Living Body, at this link is highly recommended: http://www.youtube.com/watch?v=chqwSh4ii84.

Levels of Organization

The human machine is organized at different levels, starting with the cell and ending with the entire organism (see Figure below). At each higher level of organization, there is a greater degree of complexity.

Illustrates the different levels of cellular organization within a human

The human organism has several levels of organization.


The most basic parts of the human machine are cells—an amazing 100 trillion of them by the time the average person reaches adulthood! Cells are the basic units of structure and function in the human body, as they are in all living things. Each cell carries out basic life processes that allow the body to survive. Many human cells are specialized in form and function, as shown in Figure below. Each type of cell in the figure plays a specific role. For example, nerve cells have long projections that help them carry electrical messages to other cells. Muscle cells have many mitochondria that provide the energy they need to move the body.

You can watch a video about some of the specialized cells of the human body and how they function at this link: http://www.youtube.com/watch?v=I8uXewS9dJU

An illustration of different types of human body cells

Different types of cells in the human body are specialized for specific jobs. Do you know the functions of any of the cell types shown here?


After the cell, the tissue is the next level of organization in the human body. A tissue is a group of connected cells that have a similar function. There are four basic types of human tissues: epithelial, muscle, nervous, and connective tissues. These four tissue types, which are shown in Figure below, make up all the organs of the human body.

An illustration of the four tissue types found in the human body

The human body consists of these four tissue types.

  • Connective tissue is made up of cells that form the body’s structure. Examples include bone and cartilage.
  • Epithelial tissue is made up of cells that line inner and outer body surfaces, such as the skin and the lining of the digestive tract. Epithelial tissue protects the body and its internal organs, secretes substances such as hormones, and absorbs substances such as nutrients.
  • Muscle tissue is made up of cells that have the unique ability to contract, or become shorter. Muscles attached to bones enable the body to move.
  • Nervous tissue is made up of neurons, or nerve cells, that carry electrical messages. Nervous tissue makes up the brain and the nerves that connect the brain to all parts of the body.

Organs and Organ Systems

After tissues, organs are the next level of organization of the human body. An organ is a structure that consists of two or more types of tissues that work together to do the same job. Examples of human organs include the brain, heart, lungs, skin, and kidneys. Human organs are organized into organ systems, many of which are shown in Figure below. An organ system is a group of organs that work together to carry out a complex overall function. Each organ of the system does part of the larger job.

You can watch overviews of the human organ systems and their functions at the links below.

An overview of the organ systems that make up the human body

Many of the organ systems that make up the human body are represented here. What is the overall function of each organ system?

Your body’s 12 organ systems are shown below (Table below). Your organ systems do not work alone in your body. They must all be able to work together. For example, one of the most important functions of organ systems is to provide cells with oxygen and nutrients and to remove toxic waste products such as carbon dioxide. A number of organ systems, including the cardiovascular and respiratory systems, all work together to do this.

Organ System Major Tissues and Organs Function
Cardiovascular Heart; blood vessels; blood Transports oxygen, hormones, and nutrients to the body cells. Moves wastes and carbon dioxide away from cells.
Lymphatic Lymph nodes; lymph vessels Defend against infection and disease, moves lymph between tissues and the blood stream.
Digestive Esophagus; stomach; small intestine; large intestine Digests foods and absorbs nutrients, minerals, vitamins, and water.
Endocrine Pituitary gland, hypothalamus; adrenal glands; ovaries; testes Produces hormones that communicate between cells.
Integumentary Skin, hair, nails Provides protection from injury and water loss, physical defense against infection by microorganisms, and temperature control.
Muscular Cardiac (heart) muscle; skeletal muscle; smooth muscle; tendons Involved in movement and heat production.
Nervous Brain, spinal cord; nerves Collects, transfers, and processes information.

Female: uterus; vagina; fallopian tubes; ovaries

Male: penis; testes; seminal vesicles

Produces gametes (sex cells) and sex hormones.
Respiratory Trachea, larynx, pharynx, lungs Brings air to sites where gas exchange can occur between the blood and cells (around body) or blood and air (lungs).
Skeletal Bones, cartilage; ligaments Supports and protects soft tissues of body; produces blood cells; stores minerals.
Urinary Kidneys; urinary bladder Removes extra water, salts, and waste products from blood and body; controls pH; controls water and salt balance.
Immune Bone marrow; spleen; white blood cells Defends against diseases.


  • The human body is organized at different levels, starting with the cell.
  • Cells are organized into tissues, and tissues form organs.
  • Organs are organized into organ systems such as the skeletal and muscular systems.

Explore More

Explore More I

Use this resource to answer the questions that follow.

  1. List three qualities of cells.
  2. List three functions of cells.
  3. List three functions of both epithelial and connective tissue.
  4. Name three organs of the digestive system.
  5. What is the main organ of the integumentary system?
  6. List three organs of the cardiovascular system.

Explore More II


  1. What are the levels of organization of the human body?
  2. Which type of tissue covers the surface of the body?
  3. What are the functions of the skeletal system?
  4. Which organ system supports the body and allows it to move?
  5. Explain how form and function are related in human cells. Include examples.
  6. Compare and contrast epithelial and muscle tissues.




Basic unit of structure and function of living things.
connective tissue

connective tissue

Tissue made up of cells that form the body’s structure, such as bone and cartilage.
epithelial tissue

epithelial tissue

Tissue made up of cells that line inner and outer body surfaces, such as skin.
muscle tissue

muscle tissue

Tissue made up of cells that can contract; includes smooth, skeletal, and cardiac muscle tissue.
nervous tissue

nervous tissue

Tissue made up of neurons, or nerve cells; carry electrical messages.


The structural and functional unit of the nervous system; a nerve cell.


Structure composed of more than one type of tissue that performs a particular function.
organ system

organ system

Group of organs that work together performing a specific function.


Group of cells of the same kind that perform a particular function in an organism.

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Difficulty Level:
At Grade
Date Created:
Feb 24, 2012
Last Modified:
Apr 28, 2016
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