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11.22: Evolution of Simple Cells

Difficulty Level: Basic Created by: CK-12
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What would you see if you could go back 4.5 billion years?

If you took a field trip back in time to the earliest Earth things would be very different. Everything would be very hot. What company would you have? Maybe some simple microbes. Maybe not.

Ancient Life

For the first 4 billion years of Earth history there is only a little evidence of life. Organisms were tiny and soft and did not fossilize well. But scientists use a variety of ways to figure out what this early life was like. Note that period from Earth's origin to the beginning of the Phanerozoic is called the Precambrian.

Life Begins

Life probably began in the oceans. No one knows exactly how or when. Life may have originated more than once. If life began before the Moon formed, that impact would have wiped it out. Then life would have had to originate again. Eventually conditions on Earth became less violent. The planet could support life.

The first organisms were made of only one cell (Figure below). The earliest cells were prokaryotes. Prokaryotic cells are surrounded by a cell membrane. They do not have a nucleus. Their organelles are free in the cell. The cells get their nutrients directly from the water they live in. The cells need to use these nutrients to live and grow.

E. coli (Escherichia coli) is a primitive prokaryote that may resemble the earliest cells.

The cells also needed to be able to make copies of themselves. To do this they stored genetic information in nucleic acids. The two nucleic acids are DNA (deoxyribonucleic acid) and RNA (ribonucleic acid). Nucleic acids pass genetic instructions to the next generation.

Oxygen Enters the Atmosphere

Early cells took nutrients from the water. Eventually the nutrients would have become less abundant.

Around 3 billion years ago, photosynthesis began. Organisms could make their own food from sunlight and inorganic molecules. From these ingredients they made chemical energy that they used. Oxygen is a waste product of photosynthesis. That first oxygen combined with iron to create iron oxide. As more oxygen was produced, the gas entered the atmosphere.

Some of the oxygen in the atmosphere became ozone. The ozone layer formed to protect Earth from harmful ultraviolet radiation. This made the environment able to support more complex life forms.

Early Organisms

The first organisms to photosynthesize were cyanobacteria. These organisms may have been around as far back as 3.5 billion years. Cyanobacteria are still alive today (Figure below). Now they are called blue-green algae. They are common in lakes and seas and account for 20% to 30% of photosynthesis today.

These rocks in Glacier National Park, Montana may contain some of the oldest fossil microbes on Earth.


  • cyanobacteria: Single celled prokaryotes that were extremely abundant in the Precambrian.
  • DNA (deoxyribonucleic acid): The major nucleic acid in use today. DNA stores genetic information and replicates it.
  • nucleic acid: An organic substance that stores genetic information. Nucleic acids replicate hereditary information and express it through protein synthesis.
  • prokaryote: An organism that lacks a cell nucleus or membrane-bound organelles.


  • A prokaryote has a cell membrane but otherwise organelles are loose within the cell.
  • Photosynthesis allows organisms to produce food energy with oxygen as a by-product. After photosynthesis evolved, iron oxidized and then oxygen entered the atmosphere. Ozone was created in the upper atmosphere.
  • Cyanobacteria, which are still around today, were the earliest known photosynthesizing organisms.


Use this resource to answer the questions that follow.

Cyanobacteria: Photosynthetic Prokaryotes at http://www.youtube.com/watch?v=uU00tg98Jjw (3:43)

  1. What are cyanobacteria?
  2. When did cyanobacteria dominate Earth?
  3. How does a prokaryotic cell differ from a eukaryotic cell?
  4. What are cyanobacteria responsible for?
  5. Where are cyanobacteria found?
  6. What are stromatolites?
  7. What is a heterocyst? What does it do?
  8. What is an akinete? What is its function?


  1. Compare and contrast prokaryotes and eukaryotes.
  2. Why was the development of photosynthesis so important to the evolution of life?
  3. What do we know about the first life forms?




Single celled prokaryotes that were extremely abundant in the Precambrian.
DNA (deoxyribonucleic acid)

DNA (deoxyribonucleic acid)

Major nucleic acid in use today; DNA stores genetic information and replicates it.
nucleic acid

nucleic acid

Organic substance that stores genetic information; nucleic acids replicate hereditary information and express it through protein synthesis.


Organism that lacks a cell nucleus or membrane-bound organelles.

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Difficulty Level:
6 , 7
Date Created:
Jan 04, 2013
Last Modified:
Mar 23, 2016
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