Fighting In The Dark
What a strange place to look for a cure to cancer!
underground search for new drugs
You're Going Down There?
People are fairly familiar with abundant resources leading to abundant life. But have you ever thought about places where resources are not abundant, where life is a little harder, and organisms have to come up with interesting ways to survive? Well, some scientists have as such places represent life on the edge and the chance to learn more about all the possibilities of life. Caves are such places. Sunlight, the number one energy source on the planet, isn't available to cave organisms. Of course, there is always chemical energy and chemosynthesis but even that can be restricted in some caves, and yet somehow life persists, somehow little microbial organisms show up leaving scientists to ponder the eternal question, "What the heck are they doing there?" Now, some scientists are trying to put these little organisms to work. They are seeking them out to see if any of their unique solutions to their unique environments may also be of use to humans in fighting disease.
- Caving For Cures from AMNH http://www.youtube.com/watch?v=0y9_lKq3rsc
Use the resources below to answer the following questions:
- Explain why caves are a unique environment to look for living organisms to make drugs from?
- For ecological competition to occur resources must be limited. How well do cave ecosystems match this requirement? Do you think competition levels are equal throughout caves?
- Consider the life history of microbes, they have low motility and rapid generation times. How do these factors affect competition? Do you think they would increase competition, decrease competition or have no effect?
- Why do scientists feel that environments which encourage microbial competition are good places to look for drugs?
- How do you think interspecies competition would compare to intraspecies competition for microbes in cave ecosystems?