(Opening image courtesy of Bruce Wetzel/Harry Schaefer/National Cancer Institute, http://visualsonline.cancer.gov/details.cfm?imageid=1762, colorized by Sam McCabe, and under the public domain.)
The Immune System and Disease
Lesson 24.1: Nonspecific Defenses
24.1.1 First Line of Defense
- Mechanical Barriers
- Chemical Barriers
- Biological Barriers
24.1.2 Second Line of Defense
- Inflammatory Response
Lesson 24.2: Immune Response
24.2.1 Lymphatic System
- Structures of the Lymphatic System
- Lymphatic Vessels and Lymph
- Antigen Recognition
24.2.2 Humoral Immune Response
- B Cell Activation
- Plasma Cells and Antibody Production
- Memory Cells
24.2.3 Cell-Mediated Immune Response
- T Cell Activation
- Helper T Cells
- Cytotoxic T Cells
- Regulatory T Cells
- Active Immunity
- Passive Immunity
Lesson 24.3: Immune System Diseases
24.3.2 Autoimmune Diseases
24.3.4 HIV and AIDS
- HIV Transmission
- HIV and the Immune System
- KQED: HIV Research: Beyond the Vaccine
Lesson 24.4: Environmental Problems and Human Health
24.4.1 Carcinogens and Cancer
- Types of Carcinogens
- How Cancer Occurs
- Cancer Treatment and Prevention
24.4.2 Air Pollution and Illness
- Outdoor Air Pollution
- Indoor Air Pollution
Pacing the Lessons
Use the Class Periods per Lesson table below as a guide for the time required to teach the lessons of this chapter.
Number of Class Periods
24.1 Nonspecific Defenses
24.2 Immune Response
24.3 Immune System Diseases
24.4 Environmental Problems and Human Health
- Class periods are assumed to be 60 minutes long.
See the following Web sites for appropriate laboratory activities:
1. In this virtual lab, students will gain a better understanding of antibodies by learning how they are used in medical diagnostics. (Lesson 24.2)
2. This lab demonstrates principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. (Lesson 24.2)
3. In this AP-level lab, students will learn the mechanisms of the immune system by focusing on gene variants that confer susceptibility to autoimmune disorders. (Lesson 24.3)
4. In this lab, students will role-play CDC team members preparing for a possible bioterrorist attack on a fictitious city. (Lesson 24.4)
These Web sites may also be helpful:
1. This URL is a directory of links to many useful immune system Web sites.
2. This Web site provides virtual immunology activities and tutorials.
3. Additional immunology classroom activities are described at this Web site.
4. This CDC Web site is a portal for information and data on HIV/AIDS.
5. You can access an air pollution curriculum for grades 7–12 at the URL below.
6. This URL has several detailed tutorials on cancer.