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Chapter 24: The Immune System and Disease

Difficulty Level: At Grade Created by: CK-12
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Bruce Wetzel/Harry Schaefer/National Cancer Institute, colorized by Sam McCabe. visualsonline.cancer.gov/details.cfm?imageid=1762. Public Domain.

The Immune System and Disease


Lesson 24.1: Nonspecific Defenses

24.1.1 First Line of Defense

  • Mechanical Barriers
  • Chemical Barriers
  • Biological Barriers

24.1.2 Second Line of Defense

  • Inflammatory Response
  • Leukocytes

Lesson 24.2: Immune Response

24.2.1 Lymphatic System

  • Structures of the Lymphatic System
  • Lymphatic Vessels and Lymph
  • Lymphocytes
  • Antigen Recognition

24.2.2 Humoral Immune Response

  • B Cell Activation
  • Plasma Cells and Antibody Production
  • Memory Cells

24.2.3 Cell-Mediated Immune Response

  • T Cell Activation
  • Helper T Cells
  • Cytotoxic T Cells
  • Regulatory T Cells

24.2.4 Immunity

  • Active Immunity
  • Passive Immunity

Lesson 24.3: Immune System Diseases

24.3.1 Allergies

24.3.2 Autoimmune Diseases

24.3.3 Immunodeficiency

24.3.4 HIV and AIDS

  • HIV Transmission
  • HIV and the Immune System
  • AIDS
  • KQED: HIV Research: Beyond the Vaccine

Lesson 24.4: Environmental Problems and Human Health

24.4.1 Carcinogens and Cancer

  • Types of Carcinogens
  • How Cancer Occurs
  • Cancer Treatment and Prevention

24.4.2 Air Pollution and Illness

  • Outdoor Air Pollution
  • Indoor Air Pollution

24.4.3 Bioterrorism

Pacing the Lessons

Use the Class Periods per Lesson table below as a guide for the time required to teach the lessons of this chapter.

Lesson Number of Class Periods
24.1 Nonspecific Defenses 1.0
24.2 Immune Response 2.0
24.3 Immune System Diseases 1.5
24.4 Environmental Problems and Human Health 1.0
  • Class periods are assumed to be 60 minutes long.

Online Resources

See the following Web sites for appropriate laboratory activities:

1. In this virtual lab, students will gain a better understanding of antibodies by learning how they are used in medical diagnostics. (Lesson 24.2)

2. This lab demonstrates principles of antibody-antigen binding, the secondary immune response, cross reactivity, and complement fixation. (Lesson 24.2)

3. In this AP-level lab, students will learn the mechanisms of the immune system by focusing on gene variants that confer susceptibility to autoimmune disorders. (Lesson 24.3)

These Web sites may also be helpful:

1. This URL is a directory of links to many useful immune system Web sites.

2. This Web site provides virtual immunology activities and tutorials.

3. Additional immunology classroom activities are described at this Web site.

4. This CDC Web site is a portal for information and data on HIV/AIDS.

5. You can access an air pollution curriculum for grades 7–12 at the URL below.

6. This URL has several detailed tutorials on cancer.

Chapter Outline

Chapter Summary

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