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Key Ideas

  • Single gene disorders are classified by geneticists into dominant, recessive, and sex-linked, depending on their pattern of inheritance.
  • Dominant patterns of inheritance occur when the genetic defect is a dominant allele.
  • Recessive patterns of inheritance occur when the genetic defect is a recessive allele.
  • Sex-linked patterns of inheritance occur when the genetic defect is located on the X or Y chromosome.

Overview

Building on their knowledge of dominant and recessive genes, students learn about the inheritance patterns of single gene disorders. They study and investigate dominant, recessive, and sex-linked patterns of inheritance in humans, and some of the disorders caused by each type of defect. Students simulate the expression of dominant and recessive alleles. They also examine how X-linked disorders are transmitted through successive gene rations.

Objectives

Students:

\checkmark distinguish between dominant, recessive, and sex-linked patterns of inheritance for single gene disorders.

\checkmark simulate the expression of dominant and recessive alleles.

\checkmark examine how X-linked disorders are transmitted.

Vocabulary

heterozygous, homozygous, X-linked

Student Materials

Activity 7-1: Exploring a Single Gene Disorder

  • Activity Report
  • 2 strips of colored construction paper; 2 strips of clear plastic
  • Computer with Internet connection (Optional)

Teacher Materials

Activity 7-1: Exploring a Single Gene Disorder

  • Activity Report Answer Key
  • Resource materials and Web sites providing information on genetic disorders

Advance Preparation

See Activity 7-1 in the student edition,

Activity 7-1: Exploring a Single Gene Disorder

  • Collect resource materials and identify useful Web sites.

Interdisciplinary Connection

Health Single gene disorder case histories can be discussed.

Image Attributions

Description

Authors:

Grades:

6 , 7 , 8

Date Created:

Feb 23, 2012

Last Modified:

Apr 29, 2014
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