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# 10.1: Planning

Difficulty Level: At Grade Created by: CK-12

## Key Ideas

• Genetic engineering is the process by which genes can be made to produce proteins in the laboratory by using recombinant DNA procedures.
• Recombinant DNA technology places a desired gene into a bacterial plasmid, which then expresses the protein for which it codes.
• Recombinant DNA technology is used to produce many proteins, some of which safely and effectively treat human genetic diseases.
• The goals of the Human Genome Project are to map all human genes and determine the DNA sequence of all of the chromosomes of the human genome.
• The new genetic technologies have created the need for each person to learn about genetics in order to make responsible and informed decisions on how these technologies should be used by our society.

## Overview

Students conclude their studies of human genetics through an exploration of the new genetic technologies, such as recombinant DNA. They describe and explain the importance of genetic engineering in producing proteins. They identify the procedures used in making recombinant DNA. Students discuss how bacterial plasmids and a bacterial host are used to produce a variety of useful and important proteins. Students consider potential problems inherent in the use of recombinant DNA technology. They then apply their knowledge of genetics to societal issues by participating in a mock senate hearing on genetic engineering. Students research different points of view on the new technologies, and present their recommendations on the future of genetic engineering.

## Objectives

Students:

\begin{align*}\checkmark\end{align*} describe and explain the importance of genetic engineering.

\begin{align*}\checkmark\end{align*} discuss how bacteria are used in genetic research.

\begin{align*}\checkmark\end{align*} identify and discuss the steps in making recombinant DNA.

\begin{align*}\checkmark\end{align*} pose and answer questions about the effects of recombinant DNA on individuals in society.

\begin{align*}\checkmark\end{align*} educate another person using a “big idea” from the genetics unit.

\begin{align*}\checkmark\end{align*} participate in a mock Senate hearing on whether new laws are needed to regulate gene research and genetic engineering.

## Vocabulary

cloning, gene mapping, genetic engineering, genome

## Student Materials

### Activity 9-1: Biotechnology in the U.S. Senate

• Resources about genetics, genetic diseases, biotechnology, cloning of plants, animals and humans, recombinant DNA technology, gene therapy, and ethical opinions.
• Costumes and props

## Teacher Materials

### Activity 9-1: Biotechnology in the U.S. Senate

• Resource
• Additional resources including current magazines and newspaper articles on biotechnology collected and organized into categories
• Costumes and props

See Activity 9-1 in the student edition

### Activity 9 -1: Biotechnology in the U.S. Senate

• Have students bring in current articles from newspapers, Internet resources, and magazines, as described in the “Science in the News” assignment at the beginning of the Genetics unit. These articles provide a source of current information on the pros and cons of genetic engineering.
• Assemble folders with information pertaining to each of the roles. Gather from the “Science in the News” assignments information relating to genetics.
• Research and list possible Web sites for current information on biotechnology.

## Interdisciplinary Connections

Social Studies Conduct a debate on the question, “How far should we go in biotechnology research?” Create a timeline to show the major events in genetic research over the past 50 years.

Language Arts Students write a letter to a congressional representative expressing their concerns about, or their support for the government's position on funding genetic research. Also, they write a paper on “What it means to be human.”

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Subjects:
6 , 7 , 8
Date Created:
Feb 23, 2012