Q: What is the function of the rough endoplasmic reticulum?
What is the function of the rough endoplasmic reticulum?
Rough endoplasmic reticulum is studded with ribosomes which gives it a "rough" sandpaper-like appearance. The ribosomes on the RER make proteins that are then transported from the ER in small phospholipid sacs called transport vesicles. The transport vesicles pinch off the ends of the ER. These vesicles can easily shuttle proteins between the ER and the Golgi apparatus. The RER works with the Golgi apparatus to move new proteins to their proper destinations in the cell or to the cell membrane. Proteins that are made on the RER are inserted directly into the ER and then are transported to their various cellular destinations, including the cell membrane.