Flexi Says: Tay-Sachs disease is a recessive human genetic disorder. That means only individuals with the homozygous recessive genotype, rr will be affected. Affected individuals usually die from complications of the disease in early childhood, at an age too young to reproduce. The two parents are each heterozygous (Rr) for the Tay-Sachs gene; they will not die in childhood and will be carriers of the disease gene. This deadly allele is kept in the gene pool even though it does not help humans adapt to their environment.