Flexi Says: Despite some mutations having harmful effects for individuals, mutations in a population are necessary for the population to adapt and evolve. Genetic variation is the essence of evolution. Without genetic differences among individuals, "survival of the fittest" would not be likely. Everyone would be exactly the same. With any change in the environment, the whole population would either all survive or all perish. Thus, genetic variation in a population is essential for the population to adapt to the constantly changing environment. Mutations are a source of genetic variation in a population. Mutations can produce effects that are either helpful, harmful, or neutral. Genetic disorders are caused by harmful mutations. Scientists are working to find gene therapies that can repair or replace malfunctioning genes. Someday it may be possible to cure most genetic disorders.