Flexi Says: The heart, blood vessels, and blood are the main components of the cardiovascular system, which moves nutrients, hormones, gases, and wastes to and from body cells and distributes heat to maintain homeostasis. Heart failure occurs when the pumping action of the heart is impaired, causing tissues to get inadequate transport. In cells, oxygen and other critical nutrients are quickly depleted and wastes build up to harmful levels. Without transport, the body cannot send hormone signals or take any other actions to help rebalance conditions inside the cells, disrupting homeostasis.
