Flexi Says: Humans have 23 chromosome pairs with a genome size of 6.4 nucleotide billion base pairs in each diploid cell. Human DNA polymerase replicates roughly 1,000 nucleotides per second. At that speed of DNA replication, it would take over a month to replicate its complete DNA in a single cell! In reality, it takes only about one hour because human DNA replication starts at tens of thousands of replication origins.