Flexi Says: The process of filtering substances from blood in the glomerulus is called filtration. The fluid that collects in Bowman’s space is called filtrate. It is composed of water, salts, glucose, amino acids, and urea. Larger structures in the blood—including protein molecules, blood cells, and platelets—do not pass into Bowman’s space. Instead, they stay in the main circulation. From Bowman’s space, the filtrate passes into the renal tubule. In the proximal tubule of the renal tubule, most of the reabsorption of water and salts takes place. Second filtration is required otherwise body will lose most of the essential minerals and water from the body.