Flexi Says: Eukaryotic cells are a type of cell that contains a nucleus. Eukaryotic organisms, or eukaryotes, are made up of one or more eukaryotic cells. Plant, animal and fungal cells are multicellular eukaryotes. Protists are single-celled eukaryotes. Single-celled (unicellular) organisms like amoeba are obviously composed of just one cell, whereas multicellular organisms can be composed of trillions of cells.