Summary:

  • Transcription is the first part of the central dogma of molecular biology: DNA → RNA.
  • It is the transfer of genetic instructions in DNA to messenger RNA (mRNA) Transcription takes place in three steps: initiation, elongation, and termination.
  • The new mRNA is not yet ready for translation.
  • It must go through additional processing before it leaves the nucleus.
  • This may include splicing, editing, and polyadenylation.
  • These processes modify the mRNA in various ways.
  • Such modifications allow a single gene to be used to make more than one protein.
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