Flexi Says: Normally, brain death occurs likely after about six minutes without oxygen. Brain death is defined as the irreversible loss of all functions of the brain, including the brainstem. Death of vital organs like the brain, heart or lungs but other organs of the body functions for sometime is termed as 'clinical death'. On the other hand, 'Biological death' is a formal death of the body when the whole system fails but certain organs continue to function for a while.